Ketone Supplements May Help Reduce Anxiety


Dominic D'Agostino pic
Dominic D’Agostino

Dominic D’Agostino holds a doctorate in neuroscience and physiology from the University of Medicine and Dentistry of New Jersey. In addition to his research on muscle wasting and motoneuron diseases, Dominic D’Agostino recently conducted a study on the role of exogenous ketone supplements in reducing anxiety-related behavior.

Basing their research on the evidence that nutritional ketosis can improve seizures and neurological conditions, researchers administered ketone supplements to Wistar Albino Glaxo/Rijswijk (WAG/Rij) and Sprague-Dawley (SPD) rats to study their effects on anxiety-related behavior, as measured by performance on an elevated plus maze (EPM).

The researchers found that ketone supplementation raised blood βHB levels in the two rat models and lowered anxiety-related behavior. These findings suggest that ketone supplementation could be an effective substitute for a strict ketogenic diet to achieve nutritional ketosis as an approach to treating anxiety.

The results of the study were published in the scientific journal, Frontiers in Molecular Neuroscience, in December 2016.

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